***NOTE: No Big 12 player has gone 53rd overall***
Best Big 12 Player Drafted #52: Darnell Jackson, Kansas Jayhawks, by the Miami Heat in 2008.
Jackson was drafted by the Heat and traded on draft day to the Cleveland Cavaliers, where he, interestingly enough, was teamed up with fellow class of 2008 Jayhawk (and best 56th draft pick in Big 12 history) Sasha Kaun. Jackson played one season with Cleveland and has also seen time with the Milwaukee Bucks and Sacramento Kings.
Other Notable Big 12 Players Drafted 52nd: None.
Best Non-Big 12 Player Drafted 52nd: Jarron Collins, Stanford Cardinal, by the Utah Jazz in 2001.
As far as I can remember, Collins was the first set of twins to be drafted in the NBA, followed by the Lopez', another Stanford pair, and soon to be joined by the Morris'. This fact can be refuted, but I can't think of another pair of twins to both be drafted to the NBA. But Collins has actually proved to be a serviceable backup, averaging nearly 4 points and 3 rebounds per game.
In preparation for the 2011 NBA Draft, each day until June 23 we'll count down the best Big 12 player drafted with each pick. This list only takes into account players who played in the Big 12, so it starts with the 1997 draft. In total 70 Big 12 alumni have been selected, filling 43 of the 60 possible slots.